Injection phenergan uses

G. Other important considerations in the differential diagnosis include central anticholinergic toxicity, heat stroke, drug fever injection phenergan uses and primary central nervous system (CNS) pathology. Halogenated Anesthetics: (Moderate) Halogenated anesthetics carry a possible risk for QT prolongation and torsade de pointes (TdP). Cyproheptadine: (Moderate) Additive anticholinergic effects may be seen when promethazine is used concomitantly with other drugs with antimuscarinic activity phenergan prescription like sedating H1-blockers. The risk of adverse effects such as drowsiness, dizziness, orthostatic hypotension, neuroleptic malignant syndrome, or extrapyramidal symptoms may be increased. Clemastine: (Moderate) Additive anticholinergic effects may be seen when promethazine is used concomitantly with other drugs with antimuscarinic activity like sedating H1-blockers. Clinicians should note that antimuscarinic effects may be seen not only on GI smooth muscle, but also on bladder function, the eye, and temperature regulation. Clinicians should note that antimuscarinic effects may be seen not only on GI smooth muscle, but also on bladder function, the eye, and temperature regulation. Children, dehydration, infants, neonates, Reye's syndrome Promethazine is contraindicated for use in children < desyrel over the counter 2 years of age, including infants and neonates due to the risk for fatal respiratory depression. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of PHENERGAN Injection in pediatric patients. It isn’t effective in treating the cause of symptoms or in speeding recovery, according to the National Institutes of Health (NIH). Carbetapentane; Phenylephrine; Pyrilamine: (Moderate) Drowsiness has been reported during administration of drugs containing carbetapentane. Because promethazine causes pronounced sedation, an enhanced CNS depressant effect or additive drowsiness may occur. Because promethazine causes pronounced sedation, an enhanced CNS depressant effect or additive drowsiness may occur when it is combined with other CNS depressants including sedating H1-blockers. Fosphenytoin: (Moderate) The combination of anticonvulsants (e. Use of syringes with rigid plungers or of small-bore needles might obscure typical arterial backflow if this is relied upon alone. In general, the use of a phenothiazine-type drug should be avoided in patients requiring therapy for Parkinson's disease phenergan reaction treatment unless the benefit of the drug outweighs the risk of decreased therapeutic response to levodopa or other treatments. Like other phenothiazine derivatives, promethazine is expected to have low excretion into breast can you take phenergan and benadryl together milk, and occasional short-term use is probably compatible with posing little risk provigil effect on dopamine to a nursing infant. Methadone: (Major) The need to coadminister methadone with drugs known to prolong the QT interval should be done with extreme caution and a careful assessment of treatment risks versus benefits. However, if multiple doses are to be used, the infant should be monitored for excess sedation or paradoxical CNS stimulation. Pentazocine; Naloxone: (Moderate) Because promethazine causes pronounced sedation, an enhanced CNS depressant effect or additive drowsiness may occur when it is combined with other CNS depressants including pentazocine. Since promethazine is a phenothiazine antihistamine, it should be used cautiously in patients receiving antidiabetic agents; patients should routinely monitor their blood glucose as indicated. PHENERGAN Injection may cause marked drowsiness or impair the mental or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. To avoid the possibility of physical and/or chemical incompatibility, consult specialized literature before diluting with any injectable solution or combining with any other medication. If unintentional intra-arterial injection or extravasation occurs, sympathetic block and heparinization may be useful. There are no dosing recommendations for Aristada during use of a mild to moderate CYP2D6 inhibitor. Drugs with a possible risk for QT prolongation and TdP that should be used cautiously and with close monitoring with promethazine include artemether; lumefantrine. • Prevention and control of nausea and vomiting associated with certain types of anesthesia and surgery. Due phenergan rx dosage to the close proximity of arteries and veins in the areas most commonly used for intravenous injection, extreme care should be exercised to avoid perivascular extravasation or unintentional intra-arterial injection as pain, severe chemical irritation, severe spasm of distal vessels, and resultant gangrene requiring amputation are likely under such circumstances. The phenothiazine should be immediately discontinued and appropriate supportive therapy initiated as soon as symptoms of NMS are discovered. Bladder obstruction, GI obstruction, ileus, prostatic hypertrophy, urinary retention Promethazine has substantial anticholinergic effects and a worsening of symptoms may be seen in patients with bladder obstruction, GI obstruction or ileus, benign prostatic hypertrophy, or urinary retention. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias). Drugs with a possible risk for QT prolongation and TdP that should be used cautiously provigil 20 mg and with close monitoring with promethazine include chloroquine. , ethotoin, phenytoin or fosphenytoin) and phenothiazines should be approached with caution. Precautions General Drugs having anticholinergic properties should be used with caution in patients with narrow-angle glaucoma, prostatic hypertrophy, stenosing peptic ulcer, pyloroduodenal obstruction, and bladder-neck obstruction. Department of Health and Human Services reported that 11,000 emergency room visits occurred in the United States in 2011 (the most recent year for which data is available) as the result of codeine misuse. Limited data, including some case reports, suggest that olanzapine may be associated with a significant prolongation of the QTc interval in rare instances.